Thursday, December 11, 2008
7:30AM – 8:00AM Continental Breakfast Service

Scientific Session 3: Virology
Session Chair: Dr. Preston Marx
Session Co-Chair: Dr. Adrian McDermott

8:00AM – 8:30AM Presentation: Dr. Preston Marx, Chair, Division of Microbiology and Immunology, Tulane University Health Sciences Center

8:30AM – 9:30AM

-- Gag- and Nef-specific CD4+ T cells recognize and inhibit SIV-infected macrophages early after infection, Jonah Sacha, University of Wisconsin-Madison

-- Destruction of monocyte/macrophages dictate AIDS progression in SIV infected macaques, Marcelo Kuroda, Tulane National Primate Research Center

-- Rhesus macaques infected with new and divergent SIVsmm strains: novel model for AIDS pathogenesis and vaccine research, Rajeev Gautam, Tulane National Primate Research Center

9:30AM – 10:00AM Coffee Break

10:00AM – 11:40AM

-- Increased IL-15 production is associated with higher infection of memory CD4 T cells during acute SIV infection, Joseph Mattapallil, Uniformed Services University of the Health Sciences

-- Effects of Depo-provera administration on disease progression in SIV-infected female Chinese rhesus macaques, Yvette Edghill-Spano, Southern Research Institute

-- Low dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates features of human mucosal infection by HIV-1, Brandon Keele, University of Alabama at Birmingham

-- Induction of anti-vIL-6 specific responses as a novel strategy to control KSHV-like disease in the SIV/RRV-infected rhesus macaque, Beata U. Orzechowska, Oregon Health & Science University

-- Tropism of SIV infection determines pathogenicity and induction of protective response against pathogenic SIV infection, Kazuyasu Mori, AIDS Research Center, Japan

11:40AM – 1:30PM Lunch (not included in registration fee)

Scientific Session 4: Immunology
Session Chair: Dr. R. Paul Johnson
Session Co-Chair: Dr. Marcus Altfeld

1:30PM – 2:00PM Presentation: Dr. R. Paul Johnson, Chair, Division of Immunology, New England Primate Research Center

2:00PM – 3:00PM

-- Reduced monocyte mediated inflammation and low levels of immune activation in SIV+ sooty manabeys, Kiran Mir, Seattle Biomedical Research Institute

-- Contribution of naive cells to CD4 central memory T cell homeostasis in rhesus macaques infected with SIVmac239, Afam Okoye, Vaccine and Gene Therapy Institute and the Oregon National Primate Research Center

-- Inhibition of adaptive immune responses during primary SIVagm infection does not induce an AIDS-like disease in Sabaeus African green monkeys, Roland Zahn, Beth Israel Deaconess Medical Center

3:00PM – 3:30PM Coffee Break

3:30PM – 4:00PM Presentation: Dr. Marcus Altfeld, Partners AIDS Research Center, Massachusetts General Hospital

4:00PM – 4:40PM

-- The IL-7 responsiveness of CD4+ central memory T cells is impaired in progressive SIV infection, Mukta Rohankhedkar, Vaccine and Gene Therapy Institute and the Oregon National Primate Research Center

-- CD8 T cell memory differentiation program: What dictates effector and memory heterogeneity?, Vandana Kalia, Emory University

4:40PM – 5:00PM Ceremonial celebration of Cayo Santiago’s 70th anniversary

**All invited speakers are subject to change.