Friday, December 12, 2008
7:30AM – 8:00AM Continental Breakfast Service

Scientific Session 5: Vaccines
Session Chair: Dr. Norman Letvin
Session Co-Chair: Dr. David Watkins

8:00AM – 8:30AM Presentation: Dr. Norman Letvin, Chief, Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Harvard Medical School

8:30AM – 9:30AM

-- Induction of functional T-cell responses in neutralizing antibody-triggered SIV control, Tetsuro Matano, University of Tokyo

-- Immunization with envelope-modified strains of single-cycle SIV reduces viral loads after repeated low-dose challenge with SIVmac251, Michael Alpert, Harvard Medical School

-- Maturation of SIV-specific CD8+ T cells after vaccination with SIVdeltanef, Nadine C. Salisch, New England Primate Research Center

9:30AM – 10:00AM Coffee Break

10:00AM – 10:30AM Presentation: Dr. David Watkins, Professor, University of Wisconsin-Madison, Department of Pathology and Laboratory Medicine

10:30AM – 11:10AM

-- Rhesus cytomegalovirus (RhCMV) vectors elicit strong, persistent SIV-specific CD4+ and CD8+ effector memory T cell responses that can protect vaccinated rhesus monkeys against low dose mucosal challenge with pathogenic SIVmac239, Scott Hansen, Vaccine and Gene Therapy Institute and the Oregon National Primate Research Center

-- Comparative prime-boost immunization and the role of neutralizing antibodies in protection against mucosal SHIVsf162p4 infection, Shiu-Lok Hu, Washington National Primate Research Center

11:10AM – 11:40AM Scientific Session 5b: Late breaker abstracts

11:40AM – 12:30PM Closing Remarks and Preview of Upcoming Symposium
Dr. David O’Connor, Wisconsin National Primate Research Center
Representative from New England National Primate Research Center, Host of the 27th Annual Symposium

**All invited speakers are subject to change.